Intonation Pioneers Cancer Treatments Through Collaboration

Achieve Your Drug Discovery Goals With Cost-Effective Solutions

We partner with you to deliver your drug discovery goals

We are the rapidly-growing Auxiliary Research Outsourcing, “ARO”, organization

Established in 2005, we have a solid track record of over 20+ years of delivering on time and exceeding the expectations of our valued customers.

Services

Innovate R&D with Intonation’s Expertise

Chemistry Services

Chemistry is at the heart of Intonation with over 80 chemists supported by state of the art infrastructure and analytical capabilities.

Pharmacology Services

Our unique expertise in designing and executing validated disease relevant biological assays is pivotal to support a successful hit-to-lead campaign.

In-Vitro/In-Vivo ADME

Profiling the Physio-chemical characteristics and ADME/Tox of compounds play a crucial role in the success of a drug candidate.

Integrated Drug Discovery Solutions

We offer all the relevant capabilities required to support drug discovery projects from hit identification through to candidate selection and beyond.

Intonation in Numbers

Years of Experience

sq. ft Facility

Facilities

Labs

Scientists

Research Reports

INDs

Marketed Drugs

Ph.D: M.Sc

Ph.D: M.Sc

Years of Experience

sq. ft Facility

Facilities

Labs

Scientists

INDs

Research Reports

Marketed Drugs

Ph.D: M.Sc

Ph.D: M.Sc

Our Infrastructure

We operate a 130,000 sq.ft state of the art chemistry and bioscience facility in Hyderabad India. The laboratory complex with 60 fume hoods, cell culture, screening and radioisotope laboratories which are designed to facilitate effective communication and workflow between scientists.

Our Infrastructure

We operate a 130,000 sq.ft state of the art chemistry and bioscience facility in Hyderabad India. The laboratory complex with 60 fume hoods, cell culture, screening and radioisotope laboratories which are designed to facilitate effective communication and workflow between scientists.

From the Intonation News Room

News & Case Studies

Intonation Research Laboratories, Hyderabad Collaborates with Stanford’s Innovative Medicines Accelerator (IMA), to develop treatments for cancer

by | Mar 24, 2025 | News | 0 Comments

Stanford University’s Innovative Medicines Accelerator (IMA) and Intonation Research Laboratories have partnered to develop targeted treatments for neuroendocrine...

Safe and Orally Bioavailable Inhibitor of Serine Palmitoyltransferase Improves Age-Related Sarcopenia

by | Jan 14, 2025 | News | 0 Comments

The accumulation of ceramides and related metabolites has emerged as a pivotal mechanism contributing to the onset of age-related diseases. However, small molecule...

Inhibiting de novo ceramide synthesis restores mitochondrial and protein homeostasis in muscle aging

by | Jan 14, 2025 | News | 0 Comments

Disruption of mitochondrial function and protein homeostasis plays a central role in aging. However, how these processes interact and what governs their failure in...

Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitor pathway

by | Jan 14, 2025 | News | 0 Comments

Activation of tumor suppressors for the treatment of human cancer has been a long sought, yet elusive, strategy. PTEN is a critical tumor suppressive phosphatase that...

Tetravalent SARS-CoV-2 Neutralizing Antibodies Show Enhanced Potency and Resistance to Escape Mutations

by | Jan 14, 2025 | News | 0 Comments

Neutralizing antibodies (nAbs) hold promise as therapeutics against COVID-19. Here, we describe protein engineering and modular design principles that have led to the...

Indole-3-carbinol in-vitro antiviral activity against SARS-Cov-2 virus and in-vivo toxicity

by | Jan 14, 2025 | News | 0 Comments

The effects of indole-3-carbinol (I3C) compound have been described deeply as antitumor drug in multiple cancers. Herein, I3C compound was tested for toxicity and...

Sphingolipids accumulate in aged muscle, and their reduction counteracts sarcopenia

by | Jan 13, 2025 | News | 0 Comments

Age-related muscle dysfunction and sarcopenia are major causes of physical incapacitation in older adults and currently lack viable treatment strategies. Here we find...

Testimonials

Hear it from our happy and satisfied clients

I have to say – and I am known not to make such statements easily – it was a delightful experience to work with Intonation. The chemistry work was top standard. But not only that: we are a dynamic company and we had demanding ad hoc requests to enable us meeting the project milestones faster.
The Intonation team did what in the back of my mind I expected to be impossible, and it moved us ahead of expectations in the overall program.

-VP and Head Project  Management

The analytical characterization of target xxxx is excellent. 

This request became much more complicated than we expected. Many thanks for your diligent and careful work. Our team is very impressed.

– Global Outsourcing Manager

I heard only positive news from our team about the progress of your team on the Lead Optimization, so I’m very happy with the progress of the project

CSO, European Biopharmaceutical company

I am pleased to see our collaboration progressing well, with multiple projects (in chemistry and ADME) now underway and delivering promising initial results. We are very happy with both the progress and the quality of work.

– European Biotech

Things are progressing well overall, and the report is very clear and thorough, which I appreciate.

US early-stage Biotech company

Testimonials

Hear it from our happy and satisfied clients

I have to say – and I am known not to make such statements easily – it was a delightful experience to work with Intonation. The chemistry work was top standard. But not only that: we are a dynamic company and we had demanding ad hoc requests to enable us meeting the project milestones faster.
The Intonation team did what in the back of my mind I expected to be impossible, and it moved us ahead of expectations in the overall program.

-VP and Head Project  Management

The analytical characterization of target xxxx is excellent. 

This request became much more complicated than we expected. Many thanks for your diligent and careful work. Our team is very impressed.

– Global Outsourcing Manager

I heard only positive news from our team about the progress of your team on the Lead Optimization, so I’m very happy with the progress of the project

CSO, European Biopharmaceutical company

I am pleased to see our collaboration progressing well, with multiple projects (in chemistry and ADME) now underway and delivering promising initial results. We are very happy with both the progress and the quality of work.

– European Biotech

Things are progressing well overall, and the report is very clear and thorough, which I appreciate.

US early-stage Biotech company

Corporate Social Responsibility